DNA and RNA quantitation and sizing can be done in seconds using automated capillary electrophoresis separation. The LabChip® GX Touch™ nucleic acid analyzer’s microfluidic technology generates reproducible, high-resolution data and is optimal for:
NGS library preparation (smear and fragment analysis) and quality control
RNA and DNA fragment analysis (including cell-free DNA (cfDNA), DNA isolated from FFPE samples, and PCR-free libraries)
Quantitation and qualification for CRISPR fragment analysis
Agarose gel workflows
The Comprehensive Solution for Genomic Sizing & Quantitation
Quantitate DNA and RNA sample integrity hours faster than agarose gels
Maximize rare or low-concentration samples like cfDNA, PCR-free libraries, and ChIP-seq libraries
Accurate quantitation down to 25 pg/µL for DNA smears and 0.5 pg/µL for fragments
NGS library prep analysis and QC
Flexible throughput options make it cost-efficient – 96-well or 384-well (HT) format
Data visualization options (electropherogram, virtual gel, or tabular report)
With complete analysis of genomic material in about 30 seconds, the LabChip GX Touch nucleic acid analyzer eliminates the nucleic acid quantitation workflow bottleneck. High-resolution analysis provides exact sizing and quantitation of DNA fragments and smears down to 5 bp from samples as small as 2 pg/µL.
The system offers a broad variety of DNA analysis options, including the NGS 3K assay, which provides unparalleled genomic data quality with minimal input requirements. This high degree of sensitivity also makes it the ideal instrument for gDNA, cfDNA, and PCR-free DNA quantitation, where concentrations are low, samples are precious and their preservation is essential.
When used for RNA analysis, it provides critical RNA metrics such as peak heights, peak areas, and concentration, which are used to determine an RQS (RNA Quality Score) for each sample. The RQS calculation has been validated to correlate with Agilent’s RIN (RNA Integrity Number) and follows the same 0-10 scale rating.